In addition to having to rest players for the second leg, the Giallorossi were still stinging from Thursday's controversial Europa League play-off tie with FC Porto, in which Paulo Dybala suffered a knee injury. Lucas Gourna-Douath and Assane Sala-Eddine began, but Devyne Rensch was hurt and Bryan Cristante was banned. After just one victory and two draws in ten rounds, the Ducali fell into the bottom three. Valentin Mihaila, Gabriel Charpentier, Adrian Benedyczak, Mateusz Kowalski, Alessandro Circati, and Yordan Osorio were all listed as absentees, along with Milan Djuric.

Ange-Yoan Bonny attempted to touch in Matteo Cancellieri's roll across from the left, but Gianluca Mancini made a decisive save. Then, following a powerful Cancellieri solo run, the same player poked onto the side netting.